7.1 Drugs used in obstetrics

7.1 Drugs used in obstetrics

7.1.1 prostaglandins and oxytocics

Induction and augmentation of labour

RED Dinoprostone vaginal gel 1mg and 2mg

RED Oxytocin injection 5units/mL, 10units/mL

Dinoprostone 10mg vaginal delivery system (Propess®)

Propess® (dinoprostone) 10mg vaginal delivery system is licensed and now locally approved for the initiation of cervical

ripening in patients, at term (from 38th week of gestation). It has a number of advantages over dinoprostone

gel (Prostin®) and is expected to become the product of choice for this indication where appropriate. This is in line with

recommendations from NICE in its Clinical

Guideline advice on Induction of Labour which stated use of Propess® is expected to deliver downstream savings from its

preferential use over Prostin® gel.

RED Dinoprostone vaginal pessaries 10mg

Prevention and treatment of haemorrhage

RED Carboprost injection 250 microgram/mL

RED Ergometrine injection 500 microgram/mL

RED Oxytocin with ergometrine (Syntometrine®)

Prophylaxis of postpartum haemorrhage at caesarean section

Specific Patient Group in enhanced treatment pathway, restricted use for elective caesarean section.(hospital use only)

RED Carbetocin100mcg/mL (Pabal®)

Induction of abortion – Consultant only

RED Misoprostol tablets 200micrograms [unlicensed]

7.1.1.1 Ductus arteriosus

Maintenance of patency

RED Alprostadil intravenous solution 500 microgram/mL

RED Dinoprostone 1mg/mL 0.75mL amp [unlicensed]

Closure of ductus arteriosus

RED Indometacin injection 1mg

Preterm birth risk reduction

SEE Northwest Guideline Pre Term Birth

RED Omega 3-acid-ethyl esters (Omacor®)

7.1.2 Mifepristone

RED Mifepristone tablets 200mg

7.1.3 Myometrial relaxants

RED Salbutamol solution for intravenous infusion 5mg/5mL

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