| Information on the use of immunoglobulins is included in the UK Health Security Agency's Immunoglobulin Handbook available |
| at www.gov.uk and in the Department of Health's publication Immunisation against Infectious Disease, www.gov.uk |
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| 14.5.1 Normal Immunoglobulins |
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| 14.5.2 Disease specific immunoglobulins |
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| 14.5.3 Anti-D (RhO) immunoglobulin |
| NICE guidance TA156 (August 2008) recommends routine antinatal anti-D prophylaxis should be offered to all non-sentitised |
| pregnant women who are rhesus negative.Two doses should be given: 1000-1650 units of anti-D immunoglobulin should be |
| given at 28 weeks gestation and then at 34 weeks. Alternatively a single dose of 1500 units can be given between 28 and 30 |
| weeks. |
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| RED Anti-D (Rh0) immunoglobulin injection |
| 250 units, 500 units, 1500 units, 2500 units |
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