1.2 Antispasmodics and other drugs affecting motility

1.2 ANTISPASMODICS AND OTHER DRUGS ALTERING GUT MOTILITY

1.2 Antispasmodics and other drugs altering gut motility

Useful as adjunctive treatment in non-ulcer dyspepsia, irritable bowel syndrome and diverticular disease, to reduce

intestinal motility.

GREEN Mebeverine capsules 200mg (Colofac®MR)

GREEN Mebeverine tablets135mg (prescribe as Colofac®)

GREEN Alverine Citrate capsules 60mg

GREEN Hyoscine butylbromide

tablets 10mg,

injection 20mg/mL *WARNING see link below*

*Drug Safety Update* serious adverse effects in patients with underlying cardiac disease

GREEN Peppermint oil e/c capsules

RED Peppermint water

AMBER Dicycloverine 10mg/5mL oral solution. [Use restricted to paediatrics only, for continuation when initiated

by tertiary centres.]

Metoclopramide and domperidone stimulate gastric emptying, small intestinal transit and enhance strength of oesophageal

sphincter contraction. Avoid metoclopramide in children and those under 20 years of age because of the risk of dystonic

reactions.

GREEN Domperidone - see section 4.6

GREEN Metoclopramide- see section 4.6

BACK to main chapter