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MHRA Drug Safety Updates

 

MHRA Yellow Card Scheme: please help to reverse the decline in reporting of suspected adverse drug reactions 

Items In This Category

 TitleCreatedDownload
application/pdfDrug Safety Update MHRA September 2020 PDF.pdf (279KB)24/09/2020Download
 Opioids: risk of dependence and addiction: Transdermal fentanyl patches for non-cancer pain: do not use in opioid-naive patients: Methotrexate once-weekly for autoimmune diseases: new measures to... 
application/pdfDrug Safety Update MHRA August 2020-DSU-PDF.pdf (306KB)01/09/2020Download
 Stimulant laxatives (bisacodyl, senna and sennosides, sodium picosulfate) available over-the-counter: new measures to support safe use. Clozapine and other antipsychotics: monitoring blood... 
application/pdfDrug Safety Update MHRA July-2020-DSU-PDF.pdf (203KB)31/07/2020Download
 Systemically administered VEGF pathway inhibitors: risk of aneurysm and artery dissection. Liposomal and lipid-complex formulations: name change to reduce medication errors  
application/pdfDrug Safety Update MHRA June-2020-DSU-PDF.pdf (286KB)29/06/2020Download
  
application/pdfDrug Safety Update MHRA May-2020-DSU.pdf (244KB)21/05/2020Download
  
application/pdfDrug Safety Update MHRA April-2020 PDF.pdf (194KB)28/04/2020Download
  
application/pdfDrug Safety Update MHRA March-2020-PDF.pdf (301KB)07/04/2020Download
 Esmya - licence suspended: tofacitinib [Xeljanz] - new measures to minimise risk of VTE & of serious and fatal infections: Baricitinib - risk of venous thromboembolism 
application/pdfDrug Safety Update MHRA Feb-2020-PDF.pdf (337KB)13/02/2020Download
 Ingenol mebutate gel (Picato▼): suspension of the licence due to risk of skin malignancy. Lemtrada▼ (alemtuzumab): updated restrictions and strengthened monitoring requirements following review of... 
application/pdfDrug Safety Update MHRA Jan-2020-PDF-final.pdf (261KB)29/01/2020Download
 E-cigarettes use or vaping - reporting suspected adverse reactions, including lung injury: Ondansetron - small increased risk of oral clefts following use in the first 12 weeks of pregnancy.... 
application/pdfDrug Safety Update MHRA December 2019 PDF.pdf (201KB)18/12/2019Download
 Domperidone for nausea and vomiting: lack of efficacy in children: reminder of contraindications in adults and adolescents 
application/pdfDrug Safety Update MHRA November 2019-PDF.pdf (252KB)22/11/2019Download
 Yellow fever vaccine: Carfilzomib (Kyprolis▼): risk of reactivation of hepatitis B virus:  
application/pdfDrug Safety Update MHRA October 2019 PDF.pdf (336KB)23/10/2019Download
 Ingenol mebutate gel (Picato▼): increased incidence of skin tumours seen in some clinical studies. Nivolumab (Opdivo): reports of cytomegalovirus (CMV) gastrointestinal infection or reactivation.... 
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