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6.2 Thyroid and antithyroid drugs

6.2 Thyroid and anti-thyroid drugs


    6.2.1 Thyroid hormones
        GREEN       Levothyroxine tablets 25, 50, 100 microgram
        BLACK       Levothyroxine liquid (all strengths)
 
        RED           Liothyronine injection 20 microgram  (hospital use only in thyroid emergencies)  
 
        Liothyronine tablets:  RED Traffic Light for use in: 
            > Monotherapy treatment in refractory hypothyroidism 
            > Add-on treatment for refractory hypothyroidism [Not to be used alone or in combination with levothyroxine]
        RED           Liothyronine tablets [tertroxin]
        link to RCP - Diagnosis and management of primary hypothyroidism
 
        BLACK       Thyroid extracts [unlicensed liothyronine and thyroid extra products] e.g. Armour Thyroid   
    RMOC liothyronine guidance
        BLACK       Liothyronine tablets/capsules
        Liothyronine tablets:  BLACK Traffic Light for use in: 
            > Monotherapy for the management of chronic hyperthyroidism [primary and secondary care]
            > Liothyronine therapy commenced in the private sector
            > Management of resistant depression


    6.2.2 Anti-thyroid drugs
        Carbimazole is the drug of choice, with propylthioruracil used for patients with sensitivity to carbimazole or in pregnacy.
        Warn patients that if a sore throat develops, in the first 6-8 weeks of therapy they should stop treatment and seek medical 
        advice.
        GREEN      Carbimazole tablets 5mg, 20mg
        GREEN      Propylthiouracil tablets 50mg 
 
        Partial thyroidectomy 
        Iodine may be given for 10 - 14 days before surgery.
        RED           Aqueous iodine oral solution 100mL (Lugol’s solution)
 
 
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