3.4.1 Antihistamines |
Of some value in treatment of nasal allergies, urticarial rashes, pruritus, insect bites and drug allergies. Non-sedating |
preparations are usually longer acting. |
Non-sedating antihistamines | |
Although drowsiness is rare, nevertheless patients should be advised that it can occur and may affect performance of skilled tas | (e.g. driving); excess alcohol should be avoided. | Non-sedating antihistamines should be offered first line to all patients, especially children and adolescents. | GREEN Cetirizine tablets 10mg [Consider OTC/Self care] | Cetirizine oral solution 5mg/5mL [Consider OTC/Self care] | GREEN Fexofenadine tablets 120mg, 180mg | GREEN Fexofenadine tablets 30mg | GREEN Loratadine tablets 10mg, syrup 5mg/5mL [Consider OTC/Self care] | | Sedating antihistamines | | GREEN Chlorphenamine (chlorpheniramine) tablets 4mg, syrup 2mg/5mL [Consider OTC/Self care] | Chlorphenamine (chlorpheniramine) injection 10mg/mL | |
GREEN Hydroxyzine tablets 10mg, 25mg |
GREEN Promethazine tablets 10mg, 25mg [Consider OTC/Self-care] |
Promethazine liquid 5mg/5mL |
Promethazine is RED traffic light for use in insomnia/sleep disorders see section 4.1 AMBER Alimemazine 7.5mg/5mL SF oral solution [Second line use after promethazine when initiated by tertiary centre for | indications that include insomnia/sedation]. Use restricted to paediatrics only. | |
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3.4.2 Allergen Immunotherapy |
Treatment of severe persistent allergic asthma (NICE TAG278) |
(recommended as an option by NICE in people aged 6 years and older) |
RED Omalizumab injection 150mg/mL |
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For previously treated chronic spontaneous urticaria - recommended as an option by NICE TAG 339 |
RED Omalizumab injection 150mg/mL |
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In anaphylactic shock adrenaline 1 in 1000 should be give by intramuscular injection at the doses below. |
NOTE: 1. When administering adrenaline in an emergency the Health Care Professional should base the dose on age. |
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By intramuscular injection |
Child under 6 years 150 micrograms (0.15 mL), repeated every 5 minutes if necessary |
Child 6–12 years 300 micrograms (0.3 mL), repeated every 5 minutes if necessary |
Child 12–18 years 500 micrograms (0.5 mL), repeated every 5 minutes if necessary |
Adult 500 micrograms (0.5 mL), repeated every 5 minutes if necessary |
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