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2.7 Sympathomimetics

2.7 Sympathomimetics

    2.7.1 Inotropic sympathomimetics

           Dobutamine and dopamine increase contractility of the heart with little effect on the rate, isoprenaline increases both the 
           heart rate and contractility. Hospital use only.
             
             RED     Dobutamine injection 250mg/20mL
             RED     Dopamine   injection 40mg/mL, 160mg/mL
                                               intravenous infusion 400mg in 250mL glucose 5% 
             RED     Isoprenaline injection 100mcg/mL, 2mg/mL (unlicensed) 
 
    2.7.2 Vasoconstrictor sympathomimetics
 
           Increase blood pressure by constricting peripheral vessels. Used in emergency when other methods have failed.  
           Hospital only.
            RED       Noradrenaline acid tartrate (dilute before administration)
                           sterile solution 8mg/4mL
                           sterile solution 40mg/20mL
                           (noradrenaline acid tartrate 2mg = noradrenaline base 1mg)
            AMBER Midodrinine (Bramox®) tablets 2.5mg (licensed product for postural hypotension)
 
    2.7.3 Cardiopulmonary resuscitation
 
            10mL of 1 in 10,000 adrenaline is given by central intravenous injection in cardiac arrest.
            GREEN      Adrenaline injection 1 in 10,000
 
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