11.6 TREATMENT OF GLAUCOMA

In glaucoma there is a high intraocular pressure.

Beta blockers probably reduce the rate of production of aqueous humour.

AMBER Timolol eye drops 0.25%,

AMBER Timolol 1mg/g eye gel (Tiopex®) 0.4g Unit Dose PF

(for use in selective patients only)

Prostaglandin analogue - increases uveoscleral outflow. Latanoprost is first line therapy

AMBER Latanoprost eye drops

AMBER Latanoprost unit dose preservative free eye drops

(2nd line option for those who are intolerant to preservatives)

AMBER Bimatoprost 0.01% eye drops

(2nd line use when latanoprost not effective)

Sympathomimetics probably reduce the rate of production of aqueous humour and increase its outflow.

AMBER Brimonidine eye drops 0.2%

Carbonic anhydrase inhibitors and systemic drugs reduce aqueous humour production.

AMBER Acetazolamide tablets 250mg

Acetazolamide capsules m/r 250mg

RED Acetazolamide injection 500mg

AMBER Dorzolamide eye drops 2%

AMBER Brinzolamide eye drops 10mg/ml (Azopt®)

(Restricted use only following an unsuccessful trial of dorzolamide)

Combination products

AMBER Dorzolamide 2% & timolol 0.5% eye drops (Cosopt®) *prescribe as generic*

AMBER Ganfort® eye drops (bimatoprost 0.03% & timolol 0.05% eye drops)

AMBER Azarga® eye drops brinzolamide 10mg/ml + timolol 5mg/ml

AMBER Ganfort® unit dose eye drops P/F - as an option when intolerant to preservative

AMBER Simbrinza® eye drops (brinzolomide & brimonidine) - as 3rd line option,

consultant initiation only, in patients unsuitable for surgery

AMBER Xalacom® eye drops (latanoprost 50mcg/mL/timolol 5mg/mL)

Pilocarpine and adrenaline are now outdated treatments. Use pilocarpine only for existing

patients who are stable and have no problems with its use

Miotics - open up the inefficient drainage channels.

AMBER Pilocarpine

eye drops 1%, 2%, 3%, 4%

unit dose eye drops 4%

Radiation-induced xerostomia, Sjogren’s syndrome

AMBER Pilocarpine tablets 5mg (Salagen®)
when 1st line topical agents have not been effective

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