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MHRA Drug Safety Updates
MHRA Drug Safety Updates


MHRA Yellow Card Scheme: please help to reverse the decline in reporting of suspected adverse drug reactions 

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application/pdfDrug Safety Update MHRA June 2018.pdf (186KB)03/07/2018Download
 Drug safety Update MHRA June 2018 
application/pdfMHRA Drug Safety Update May 2018.pdf (153KB)04/06/2018Download
 Valproate medicines (Epilim▼, Depakote▼): Pregnancy Prevention Programme materials online. Braltus (tiotropium): risk of inhalation of capsule if placed in the mouthpiece of the inhaler.  
application/pdfDrug Safety Update MHRA April 2018 (267KB)24/04/2018Download
 Drug Safety Update MHRA April 2018 
application/pdfMHRA DSU March 18-PDF.pdf (274KB)09/03/2018Download
 Drug Safety Update MHRA March 2018. daclizumab, esmya, headlice 
application/pdfDrug Safety Update MHRA February 2018 PDF.pdf (278KB)13/02/2018Download
 Misoprostol vaginal delivery system (Mysodelle): reports of excessive uterine contractions (tachysystole) unresponsive to tocolytic treatment. Mycophenolate mofetil, mycophenolic acid: updated... 
application/pdfDrug Safety Update January 2018.pdf (301KB)09/01/2018Download
 Daclizumab (Zinbryta▼) and risk of severe liver injury. Recombinant human erythropoietins: very rare risk of severe cutaneous adverse reactions. Drug-name confusion: reminder to be vigilant for... 
application/pdfDrug Safety Update MHRA December 2017 (421KB)15/12/2017Download
 Cladribine (Litak, Leustat) for leukaemia, Gadolinium-containing contrast agents, Radium-223 dichloride (Xofigo▼), Eluxadoline (Truberzi ▼): 
application/pdfDrug Safety Update MHRA November 2017 pdf. (357KB)27/11/2017Download
 Gentamicin: potential for histamine-related adverse drug reactions with some batches, Quinine: reminder of dose-dependent QT-prolonging effects; updated interactions, Oral tacrolimus products:... 
application/pdfDrug Safety Update MHRA October pdf.pdf (246KB)27/10/2017Download
 Methylprednisolone inj medicines containing lactose Gabapentin: risk of severe respiratory depression Clozapine: reminder of potentially fatal risk of intestinal obstruction, 
application/pdfDrug safety Update MHRA Sept-pdf.pdf (230KB)27/10/2017Download
 Miconazole (Daktarin) OTC oral gel contra-indications in patients taking warfarin. Loperamide: reports of serious cardiac adverse reactions with high doses of loperamide associated with abuse or... 
application/pdfDrug Safety Update MHRA August PDF.pdf (260KB)27/10/2017Download
 Ibrutinib (Imbruvica▼): reports of ventricular tachyarrhythmia; risk of hepatitis B reactivation and of opportunistic infections Corticosteroids: risk of central serous chorioretinopathy with... 
application/pdfDrug Safety Update MHRA July 2017 PDF.pdf (229KB)26/07/2017Download
 Daclizumab (Zinbryta▼) and risk of severe liver injury, Bendamustine (Levact, Nivolumab (Opdivo▼), pembrolizumab (Keytruda▼): reports of organ transplant rejection 
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