| 4.2.1 Antipsychotic drugs |
Link to Suggested Monitoring Requirements of High Risk Drugs
Used for conditions such as schizophrenia or in the short term to calm disturbed patient. Other less common uses are: treatment of nausea and vomiting, choreas, motor tics and intractable hiccup. Benperidol is specifically used for deviant antisocial sexual behaviour, to be initiated by a consultant.
|
| RED Benperidol | | tablets 250mcg | |
| |
Pronounced sedative effects
|
| GREEN Chlorpromazine | | tablets 10mg, 25mg, 50mg, 100mg | | syrup 25mg/5mL , syrup 100mg/5mL | |
| GREEN Promazine | | tablets 25mg, 50mg | | oral solution 25mg/5mL | | oral solution 50mg/5mL | |
| |
| Fewer sedative effects |
| GREEN Haloperidol | | tablets 1.5mg, 5mg, 10mg | | capsules 500 micrograms | | oral liquid 2mg/mL | | injection 5mg/mL | |
GREEN Sulpiride tablets 200mg
|
| AMBER Flupentixol dihydrochloride | | tablets 3mg | |
| AMBER Trifluoperazine | | (LCFT) tablets 1mg, 5mg | | oral solution 5mg/5mL | |
| AMBER Zuclopenthixol dihydrochloride | | tablets 2mg, 10mg | |
| |
| |
|
Atypical antipsychotics |
To be started by specialists only.
| A shared care protocol is also available which outlines both the specialists and the GPs responsibilities - click here to access it.
| | | Quetiapine XL formulation
| The Drugs & Therapeutics Committee reviewed the current activity on the prescribing of the prolonged release form of Quetiapine. This formulation was approved by D&T in March 2009 subject to a prescribing guideline and initiation by a consultant. In light of the dramatic increase in the use of this product the D&T committee have made the decision to introduce an approval process. Quetiapine will become generic in 2012 and the current position regarding this formulation is unclear but it may be available as a generic product. This will place a significant cost burden on our primary care colleagues which in the current economic climate is open to challenge.
| | | | | AMBER Amisulpride
| SHARED CARE tablets 50mg, 200mg
| | liquid 100mg/mL |
| AMBER Aripiprazole tablets 10mg, 15mg, 30mg (consultant initiation only)
| SHARED CARE Aripiprazole orodispersible tablets 10mg, 15mg (for use only when swallowing difficulties)
| | | RED Aripiprazole tablets 10mg, 15mg, 30mg
| | (consultant use only for alternating hemiplegia) | | RED Clozapine tablets 25mg, 100mg (consultant only)
|
| AMBER Olanzapine tablets 2.5mg, 5mg, 7.5mg, 10mg, 15mg
| | SHARED CARE oro-dispersible 5mg, 10mg tablets | | | RED Olanzapine injection 5mg/mL
|
| AMBER Quetiapine
| | SHARED CARE tablets 25mg, 100mg, 150mg, 200mg | | m/r tablets 50mg, 200mg, 300mg, 400mg | | m/r tablets to be prescribed by brand. | | Brancico® XL 150mg, XL 200mg, XL 300mg, XL 400mg tablets [PRESCRIBE BY BRAND] | | Zaluron XL tablets, Sondate XL tablets | |
| | AMBER Risperidone | | SHARED CARE tablets 500 micrograms,1mg, 2mg, 3mg, 4mg | | Quicklets® 500 micrograms, 1mg, 2mg | | liquid 1mg/mL | | AMBER | SHARED CARE Zotepine tablets 25mg, 50mg 100mg (consultant initiation only)
| | | AMBER Cariprazine [Reagila®]
| SHARED CARE capsules 1.5mg, 3mg, 4.5mg, 6mg
| | [Only to be used as second-line therapy (where clozapine is not appropriate] where predominantly negative | | symptoms have been identified as an important feature - See Shared Care Guideline] | RED Lurasidone (Latuda®)
| | tablets fc 18.5mg, 37mg, 74mg | | Specialist service use only | | | | | Click here for the New Medicine Recommendation for Lurasidone | | | | back to main chapter |
All material in this section is aimed at health care professionals, but is information currently held in the public domain, members of the
| public seeking advice on medicine-related matters are advised to speak with their GP, pharmacist, nurse or contact NHS111 Service
| | Email: info.elmmb@nhs.net | | | Copyright© 2016 - 2023 East Lancashire Medicines Management Board.
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| | | |
