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4.1 Hypnotics and anxiolytics

4.1 Hypnotics and anxiolytics

4.1.1 Hypnotics - for short term use only

Try to avoid. If needed, use for 1-3 days only. Do not give on discharge from hospital. Hypnotics are only licensed for short term 
use. On specialist advice only, some patients with long term psychiatric problems may require long term use.
GREEN      Temazepam
                   tablets 10mg 
                   elixir 10mg/5mL
AMBER      Nitrazepam
                   tablets 5mg
                   oral suspension 2.5mg/5mL
GREEN       Zopiclone tablets 3.75mg, 7.5mg  
GREEN       Zolpidem tablets 5mg, 10mg - in line with NICE TA 77- short term use only. 
Chloral Hydrate for paediatric sedation
RED           Chloral hydrate liquid 500mg/5mL
Melatonin which is unlicensed in the UK, has been used in the treatment of sleep disorders in children with visual impairment,
cerebral palsy, and autism.  The long term safety and efficacy of melatonin is unclear. 
RED           Melatonin capsules 500micrograms, 1mg, 3mg, 5mg (unlicensed) 

4.1.2 Anxiolytics

Use at lowest dose for shortest time possible. Long term use should be avoided except on specialist advice.  Chlordiazepoxide is 
also used in a reducing dose regimen for the management of acute alcohol withdrawal.
GREEN      Chlordiazepoxide 
                   capsules 5mg, 10mg
GREEN      Diazepam
                   tablets 2mg, 5mg, 10mg  
                   syrup 2mg/5mL
                   injection 10mg/2mL
                   suppositories 10mg
GREEN      Lorazepam tablets 1mg 
RED           Lorazepam injection 4mg/mL

All material in this section is aimed at health care professionals, but is information currently held in the public domain, members of the  
public seeking advice on medicine-related matters are advised to speak with their GP, pharmacist, nurse or contact NHS111 Service 
 Email: info.elmmb@nhs.net
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